Two Tales (Tails) of SAMHD1 Destruction by Vpx
نویسندگان
چکیده
منابع مشابه
Degradation of SAMHD1 by Vpx Is Independent of Uncoating.
UNLABELLED Sterile alpha motif domain and HD domain-containing protein 1 (SAMHD1) restricts human immunodeficiency virus type 1 (HIV-1) replication in myeloid and resting T cells. Lentiviruses such as HIV-2 and some simian immunodeficiency viruses (SIVs) counteract the restriction by encoding Vpx or Vpr, accessory proteins that are packaged in virions and which, upon entry of the virus into the...
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ژورنال
عنوان ژورنال: Cell Host & Microbe
سال: 2015
ISSN: 1931-3128
DOI: 10.1016/j.chom.2015.03.013